Last updated November 9th, 2020

If you require a copy of any of our publications for academic use, please contact me (John) directly for an author’s personal copy. I’m also happy to talk about any of our work, or provide additional information about our experimental work (although we pride ourselves on detailed and readily reproducible experimentals!). Our Op-Eds, letters to editors, and various releases to the public are found under our “Outreach” tab.


Trant Team members’ names are italicizedUndergraduate trainees are underlined. Mine is bolded. Corresponding authorships are indicated with asterisks (*). 

  • 2021
  • 2020
  • 2019
  • 2018
  • 2017
  • Patents
  • John's Papers from his BSc, PhD, & PDFs

56. Wen, X.; Wen, G.; Li, W.; Zhao, Z.; Duan, X.; Yan, W.; Trant, J.F.* Li, Y* “High Yield Fluorescent Carbon Dots: Specific “Off-On” Sensing of Co2+ and EDTA, Bioimaging, and Metabolism in vivo” Accepted in Materials Science and Engineering C, February 26, 2021.

55. Tahir, N.; Shahbazi, F.; Rondeau-Gagné, S.*; Trant, J.F.* “The Biosynthesis of the Cannabinoids” Accepted in the Journal of Cannabis Research on January 7th, 2021.

54. Shakourian-Fard, M.*; Taimoory, S.M.*; Ghenaatian, H.R.; Kamath, G.; Trant, J.F.* “A DFT Study of the Adsorption of Deep Eutectic Solvents onto Graphene and Defective Graphene Nanoflakes” Accepted in the Journal of Molecular Liquids, November 20, 2020. DOI: 10.1016/j.molliq.2020.114850

53. Li, W.; Zhao, H.; Wen, X.; Yan, W. Trant, J.F.*, Li, Y Acid-Triggered Self-Assembled Egg White Protein-Coated Gold Nanoclusters for Selective Fluorescent Detection of Fe3+, NO2-, and Cysteine” Accepted in ACS Applied Nano Materials, November 11, 2020.DOI: 10.1021/acsanm.0c02358

52. Taimoory, S.M.; Cataldo, V.A.; Schäfer, A.; Trant, J.F.*; Guterman, R.* “Not-so-innocent anions determine the mechanism of cationic alkylators” Accepted in Chemistry – a European Journal November 2, 2020. DOI: 10.1002/chem.202004208

51. Askari, F.; Rahdar, A.*; Dashti, M.; Trant, J.F.* “Detecting mercury (II) and thiocyanate using “turn-on” fluorescence of graphene quantum dots” the Journal of Fluorescence, 2020, 30 1181-1187. DOI: 10.1007/s10895-020-02586-z.

50. Shahbazi, F.; Grandi, V.; Banerjee, A.Trant, J. F.*, Cannabinoids and cannabinoid receptors: The story so far. iScience 2020, 101301. DOI:


49. Rahdar, A.*; Hajinezhad, M. R.*; Nasri, S.; Beyzaei, H.; Barani, M.; Trant, J. F.*, The synthesis of methotrexate-loaded F127 microemulsions and their in vivo toxicity in a rat model. Journal of Molecular Liquids, 2020, 313, 113449. DOI: (edited) 

48. Puttreddy, R.; Taimoory, S.M.; Dashti, M.; Twum, K.; Pan, F.; Rissanen, K.*; Trant, J.F.*; Beyeh, N.K.* “Bringing a Molecular Plus One: Synergistic Binding Creates Guest-Mediated Three Component Complexes” Accepted in the Journal of Organic Chemistry, March 16, 2020. 85, 5884-5894. DOI: 10.1021/acs.joc.0c00220

47. Noura, M.; Rahdar, A.*; Taimoory, S.M.; Hayward, J.J.; Sadraei, S.I.Trant, J.F.* “Effect of aluminium-doped boron-nitride nanotube architecture on hydrogen adsorption: A first-principles DFT examination” Accepted in the International Journal of Hydrogen Energy202045, 11176-11189 DOI: 10.1016/j.ijhydene.2020.02.053

46. Pérez-Escalante, E., González-Olivares, L. G.; Castañeda-Ovando, A.; Salazar-Pereda, V.; Trant, J.F.; Bautista-Ávila, M.; Alatorre-Santamaría, S.* “Green, microwave-assisted synthesis of O-perbutirylated-alkyl-glycosides” Proceedings2020, 41, 42 DOI: 10.3390/ecsoc-23-06500.

45. Ménard, A.D.*; Trant, J.F.* “Academic lab safety: A narrative review and call for action” Nature Chemistry 202012, 17-25. DOI:10.1038/s41557-019-0375-x.

FREE LINK FOR EVER (Read only online, not printable) Thanks Nature Chem!

44. Rahdar, A.*; Beyzaei, H.; Saadat, M.; Yu, X.; Trant, J.F.* “Synthesis, physical characterization, antifungal and antibacterial activity of oleic acid-capped nanomagnetite and cobalt-doped nanomagnetite” Canadian Journal of Chemistry 202098, 34-39. DOI: 10.1139/cjc-2019-0268

43. Meister, D.; Ure, D.; Awada, A.; Mutus, B.*; Trant, J.F.* “Covalently Functionalized Sawdust for the Remediation of Phosphate from Agricultural Wastewater” Accepted ACS Sustain. Chem. Eng20197, 20139-20150. 10.1021/acssuschemeng.9b06073

42. Bakht, M. K.; Lovnicki, J.M.; Tubman, J.; Stringer, K.F.; Chiaramonte, J.; Reynolds, M.R.; Derecichei, I.; Ferraiuolo, R.-M.; Fifield, B.-A.; Lubanska, D.; Oh, S. W.; Cheon*, G. J.; Kwak, C.; Jeong, C.W.; Kang, K. W.; Trant, J.F.; Morrissey, C.; Coleman, I.M.; Wang, Y.; Ahmadzadehfar, H.*; Dong, X.; Porter, L. A.* “Differential gene expression of glucose transporters and hexokinases in PSMA suppressed prostate cancers with neuroendocrine and double negative gene signatures is associated with higher glucose uptake” Journal of Nuclear Medicine, 2020, 61, 904-910. DOI: 10.2967/jnumed.119.231068

41. Ferraiuolo, R.-M.; Meister, D.; Leckie, D.; Dashti, M.; Franke, J.; Porter, L.A.*; Trant, J.F.* “Neuro and hepatic toxicological profile of (S)-2,4-diaminobutyric acid in embryonic, adolescent and adult zebrafish” Accepted to Journal of Applied Toxicology, 201939, 1568-1577. DOI: 10.1002/jat.3840

40. Shakourian-Fard,* M.; Kamath, G.; Taimoory, S.M.Trant, J.F.* “Calcium-ion batteries: Identifying ideal electrolytes for next generation energy storage using computational analysis” Journal of Physical Chemistry C, 2019, 123, 15885-15896. DOI: 10.1021/acs.jpcc.9b01655

39. Pan, F.*; Dashti, M.; Reynolds, M.R.; Rissanen, K.; Trant, J.F.*; Beyeh, N.K.* “Halogen bonding and host-guest chemistry between  N-alkyl ammonium resorcinarene halides, diiodoperfluorobutane and neutral guests” Beilstein Journal of Organic Chemistry, 201915, 947-954. (Invited) DOI: 10.3762/bjoc.15.91

38. Rahdar, S.; Rahdar, A.; Ahmadi, S.; Trant, J.F.* “Adsorption of bovine serum albumin (BSA) by bare magnetite nanoparticles with surface oxidative impurities that prevent aggregation” Canadian Journal of Chemistry2019, 97, 577-583. 10.1139/cjc-2019-0008.

37. Askari, F.; Rahdar, A.*; Trant, J.F.* “Cysteine-functionalized quantum dots are fluorescent sensors able to discriminate between the enantiomers of tryptophan” Sensing and Bio-Sensing Research201922, 100251 (Open Access courtesy of Elsevier).


36. Meister, D.; Taimoory, S.M.Trant, J.F.* “Synthetic amino acids for the treatment of MHC Type II diseases history and perspectives” Peptide Science2018, 111 (1), e24058. Special issue celebrating 150 years of Canadian peptide science. (Invited). DOI: 10.1002/pep2.24058 COVER PICTURE! OPEN ACCESS ALL OF 2019 THANKS TO WILEY AND THE AMERICAN PEPTIDE SOCIETY!

35.  Shakourian-Fard, M.*; Taimoory, S. M.*; Semeniuchenko, V.; Kamath, G.; Trant, J.F.* “The Effect of Ionic Liquid Adsorption on the Electronic and Optical Properties of Fluorographene Nanosheets” Journal of Molecular Liquids, 2018268, 206-214. DOI: 10.1016/j.molliq.2018.07.054.

33. Puttreddy, R.; Beyeh, N.K.; Taimoory, S. M.; Meister, D.Trant, J.F.*; Rissanen, K.* “Host-Guest Complexes of Conformationally Flexible C-hexyl-2-Bromoresorcinarene and Aromatic N-oxides: Solid-state, Solution and Computational Studies” Beilstein Journal of Organic Chemistry201814, 1723-1733. DOI: 10.3762/bjoc.14.146. (Invited)

32. Taimoory, S. M.; Rahdar, A.*; Aliahmad, M.*; Sadeghfar, F.; Hajinezhad, M.R.; Jahantigh, M.; Shahbazi, P.; Trant, J. F.*, “The synthesis and characterization of a nanomagnetite with potent antibacterial activity and low mammalian toxicity” Journal of Molecular Liquids 2018265, 96-104. DOI: 10.1016/j.molliq.2018.05.105.

29. Taimoory, S. M.; Sadraei, S. I.Fayoumi, R.; Nasri, S.; Revington, M.; Trant, J. F.* “Preparation and Characterization of a Small Library of Thermally-Labile End-Caps for Variable-Temperature Triggering of Self-Immolative Polymers” Journal of Organic Chemistry 2018, 83, 4427-4440. DOI: 10.1021/acs.joc.8b00135

28. Sadraei, S.I.; St-Onge, B.; Trant, J.F.* “Recent Advances in the Application of Carbohydrates as Renewable Feedstocks for the Synthesis of Nitrogen-Containing Compounds” Chapter in: Green Chemical Processes, Advances in Education. DeGruyter, 2018. Accepted and In Press. (Invited). DOI: 10.1515/psr-2018-0074

27. Smith, L.J.; Taimoory, S.M.; Tam, R.Y.; Baker, A.E.G.; Binth Mohammad, N.; Trant, J.F.*, Shoichet, M.S.* “Diels-Alder Click-Crosslinked Hydrogels with Increased Reactivity Enable 3D Cell Encapsulation” Biomacromolecules, 201819, 926-935. DOI: 10.1021/acs.biomac.7b01715.

26. Beyeh, N.K.*; Díez, I.;  Taimoory, S.M.Meister, D.; Feig, A.; Trant, J.F.*; Ras, R.H.A.*; Rissanen, K.* “High-affinity and selective detection of pyrophosphate in water by a resorcinarene salt receptor” Chemical Science20189, 1358-1367. DOI: 10.1039/C7SC05167K .

25. Turunen, L.; Pan, F.*; Beyeh, N.K.*; Trant, J.F.; Ras, R.H.A.; Rissanen, K.* “Bamboo-like Chained Cavities and Other Halogen-Bonded Complexes from Tetrahaloethynyl Cavitands with Simple Ditopic Halogen Bond Acceptors” Crystal Growth and Design201818, 513-520. DOI: 10.1021/acs.cgd.7b01517 (Invited)

24. Puttreddy, R.; Beyeh, N.K.; Jurcek, P.; Turunen, L.; Trant, J.F.; Ras, R.H.A.; Rissanen, K.* “Host-guest complexes of C-propyl-2-bromoresorcinarene with aromatice-N-oxides” Supramolecular Chemistry, 201830, 445-454. DOI: 10.1080/10610278.2017.1414217.

23. Sadraei, S. I.Reynolds, M. R.; Trant, J.F.* “The synthesis and biological characterization of acetal-free mimics of the tumour-associated carbohydrate antigens” Advances in Carbohydrate Chemistry and Biochemistry201774, 137-237. DOI: 10.1016/bs.accb.2017.10.003.

TACA antigens

21. Turunen, L.; Pan, F.; Beyeh, N. K.; Raatikainen, K.; Trant, J. F.; Ras, R.H.A.; Rissanen, K.*, “Halogen-bonded solvates of tetrahaloethynyl cavitands” CrystEngComm 201719, 5223-5229. DOI: 10.1039/C7CE01118K.

Table of Contents Graphic showing solvent encapsulation in a resorcinarene capsule

20. Puttreddy, R.; Beyeh, N. K.; Ras, R. H. A.; Trant, J. F.; Rissanen, K.*, “Endo-/exo– and halogen-bonded complexes of conformationally rigid C-ethyl-2-bromoresorcinarene and aromatic N-oxides” CrystEngComm 201719, 4312-4320.  DOI: 10.1039/C7CE00975E.

Graphical abstract: Endo-/exo- and halogen-bonded complexes of conformationally rigid C-ethyl-2-bromoresorcinarene and aromatic N-oxides

19. Taimoory, S. M.; Rahdar, A.; Aliahmad, M.; Sadeghfar, F.; Hashemzaei, M.; Trant, J. F.*, “Importance of the inter-electrode distance for the electrochemical synthesis of magnetite nanoparticles: synthesis, characterization, and cytotoxicity” e-Journal of Surface Science and Nanotechnology201715, 31-39. DOI: 10.1380/ejssnt.2017.31.

1. 2014 Gillies, E.R.; Ferrari, L.; McEachran, M.; Trant, J.F.; Sran, I. “Polymer-Drug Conjugate Based on a Polyisoolefin-Based Copolymer” European patent application EP141956653.

2. 2014 Gillies, E.R.; Fan, B.; Trant, J.F.; Wong, A. “Stimuli-responsive polyglyoxylates as biodegradable polymers” US Provisional patent 61/989,089.

3. Ragogna, P.; Gillies, E.R.; Cuthbert, T.; Trant, J.F. “Increasing the hydrophilicity of phosphonium polymers to increase antibacterial activity and decrease hemolytic activity” US Provisional patent: #62/511,821



34. Cuthbert, T.J.; Hisey, B.; Harrison, T.D.; Trant, J.F., Gillies, E.R.; Ragogna, P.J.* “Surprising Antibacterial Activity and Selectivity of Hydrophilic Polyphosphoniums Featuring Sugar and Hydroxyl Substituents” Angewandte Chemie International Edition, 201857, 12707-12710. VIP Paper (Top 5% importance of those published in ACIE as determined by editor). DOI: 10.1002/anie.201806412

31. Badilov, D.; Rycek, L.; Trant, J.F.; Froese, J.; Murphy, B.; Hudlicky, T.* “Chemoenzymatic Approach to Tetrodotoxin: Synthesis of Fukuyama's, Alonso's, and Sato's Advanced Intermediates” Angewandte Chemie International Edition201857, 10994-10998. VIP PAPER (Top 5% importance of those published in ACIE as determined by editor). DOI: 10.1002/anie.201804602 COVER PICTURE!!!

30. Fan, B.; Yardley, R.E.; Trant, J.F.; Borecki, A.; Gillies, E.R.*, "Tuning the hydrophobic cores of self-immolative polyglyoxylate assemblies" Polymer Chemistry20189, 2601-2610. DOI: 10.1039/C8PY00350E


22. Fan, B.; Trant, J. F.; Hemery, G.; Sandre, O.; Gillies, E. R.*, "Thermo-Responsive Self-Immolative Nanoassemblies: Direct and Indirect Triggering." Chemical Communications (Cambridge) 201753, 12068-12071. DOI:  10.1039/c7cc06410a COVER PICTURE!

Table of contents graphic showing the magnetic-catalyzed disassembly of a self-immolative particle


18. Fan, B.; Trant, J. F.; Gillies, E. R.*, “End-capping strategies for triggering end-to-end depolymerization of polyglyoxylates” Macromolecules 201649 (24), 9309-9319. DOI: 10.1021/acs.macromol.6b02320.

17. Trant, J.F.; Jain, N.; Mazzuca, D.M.; McIntosh, J.T.; Haeryfar, S.M.M.; Lecommandoux, S.; Gillies, E.R.* “Synthesis, self-assembly, and immunological bioactivity of α-galactose-functionalized dendron-lipid amphiphiles.” Nanoscale20168, 17694-17704. DOI: 10.1039/c6nr05030a.

16 .Fan, Bo; Trant, J.F.; Yardley, R.; Pickering, A.; Lagugne-Labarthet, F.; Gillies, E.R.* “Photocontrolled degradation of stimuli-responsive poly(ethyl glyoxylate): Differentiating features and traceless ambient depolymerization” Macromolecules201649, 7196-7203. DOI: 10.1021/acs.macromol.6b01620.

15. Naoum, R.; Séguin, J.P.; Trant, J.F.; Frampton, M.; Hudlicky, T.; Zelisko, P.M.* "A Chemoenzymatic Route to Chiral Siloxanes: A Step Towards the Enzymatic Synthesis of Chiral Silicone Polymers" Tetrahedron2016, 72, 4027-4031. DOI: 10.1016/j.tet.2016.05.032.

14. Trant, J. F.; Abd Rabo Moustafa, M. M.; Sran, I.; Gillies, E. R.* "Polyisobutylene-paclitaxel conjugates with pendant carboxylic acids and polystyrene chains: Towards multifunctional stent coatings with slow drug release." Journal of Polymer Science Part A: Polymer Chemistry2016, 54, 2209-2219. DOI: 10.1002/pola.28094.


13. Peyret, A.; Trant, J.F.; Bonduelle, C.V.; Jain, N.; Lecommandoux, S.; Gillies, E.R.* "Synthetic glycopolypeptides: Synthesis and Self-Assembly of Poly(γ-benzyl-L-glutamate)-Glycosylated Dendron Hybrids." Polymer Chemistry2015, 6, 7902-7912. DOI: 10.1039/C5PY01060H.

12. Trant, J. F.; Sran, I.; de Bruyn, J. R.; Ingratta, M.; Borecki, A.; Gillies, E. R.* "Synthesis and Properties of Arborescent Polyisobutylene Derivatives and a Paclitaxel Conjugate: Towards Stent Coatings with Prolonged Drug Release" European Polymer Journal 2015, 72, 148-162. DOI: 10.1016/j.eurpolymj.2015.09.012.

11. Trant, J.F.; Sran, I.; McEachran, M.; Turowec, B.; de Bruyn, J.R.; Gillies, E.R.* "Covalent polyisobutylene-paclitaxel conjugates for controlled release from potential vascular stent coatings." ACS Applied Materials and Interfaces 2015, 7, 14506-14517. DOI: 10.1021/acsami.5b04001.

10. McEachran, M. J.; Trant, J. F.; Sran, I.; de Bruyn, J. R.; Gillies, E. R.* "Carboxylic acid functionalized butyl rubber: synthesis, characterization and physical properties." Industrial & Engineering Chemistry Research 2015, 54, 4763-4772. DOI: 10.1021/acs.iecr.5b00421.


9. Fan, B., Trant, J.F., Wong, A.D., Gillies E.R.* "Polyglyoxylates: A versatile class of triggerable self-immolative polymers from readily accessible monomers." Journal of the American Chemical Society2014, 136, 10116-10123. DOI: 10.1021/ja504727u

8. Trant, J.F., Ho, H., Hudlicky, T.* "The Chiro-Inositols and related cyclitols as chiral monomers for polymerization: Expansion of a family of chiral polymers" Synlett2014, 25, 2360-2364. DOI: 10.1055/s-0034-1378563


7. Trant, J.F.; Froese, J.; Hudlicky, T.* "Enzymatic oxidation of para-substituted arenes: access to new non-racemic chiral metabolites for synthesis" Tetrahedron: Asymmetry 2013, 24, 184-190. DOI: 10.1016/j.tetasy.2013.01.002.

6. Trant, J.F.; Hudlicky, T.* "Ring-opening of hindered cyclic epoxides with potassium carboxylates in the presence of conjugate acids" Canadian Journal of Chemistry2013, 91, 1179-1185. DOI: 10.1139/cjc-2013-0386.

5. Trant, J.F.; Capiciotti, C.; Biggs, R. A.; Ben, R.N.* "Development of highly active small molecule inhibitors of ice recrystallization" RSC Advances 2013, 3, 26005-26009. DOI: 10.1039/C3RA43835J.


4. Balcerzak, A.K.; Ferreira, S.S.; Trant, J.F.; Ben, R.N.* "Structurally diverse disaccharide analogs of antifreeze glycoproteins and their ability to inhibit ice recrystallization." Bioorganic & Medicinal Chemistry Letters 2012 22, (4) 1719-1721. DOI: 10.1016/j.bmcl.2011.12.097.

3. Trant, J.F.; Belding, L.; Dudding, T.; Hudlicky, T.* "Application of D-Chiro-inositol as a chiral template for the Diels-Alder reaction" Helvetica Chimica Acta, 2012, 95, 2026-2035. (Invited contribution) DOI: 10.1002/hlca.201200432.


2. Capiciotti, C.J.; Trant, J.F.; Leclère, M.; Ben, R.N.* "Synthesis of C-linked triazole-containing AFGP analogues and their ability to inhibit ice recrystallization." Bioconjugate Chemistry. 2011, 22, (4), 605-616. DOI: 10.1021/bc100394k.


1. Lemay, M.; Trant, J.; Ogilvie, W.W.* (2007) "Hydrazide Catalysed 1,3-dipolar nitrone cycloadditions." Tetrahedron2007, 63 (47) 11644-11655. DOI: 10.1016/j.tet.2007.08.110.

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